ГоловнаАрхiв номерiв2018Том 26, випуск 2 (95)Проблема диагностики и терапии аутоиммунных энцефалитов
Назва статтi Проблема диагностики и терапии аутоиммунных энцефалитов
Автори Єгоркіна Ольга Вікторівна
Волошина Наталія Петрівна
З рубрики ПРОБЛЕМНІ СТАТТІ
Рiк 2018 Номер журналу Том 26, випуск 2 (95) Сторінки 5-12
Тип статті Наукова стаття Індекс УДК 616.831-002-07.08:612.017.1 Індекс ББК -
Анотацiя Аутоиммунные энцефалиты (АЭ) — это неврологическое заболевание, характеризующееся поражением преимущественно серого вещества, в патогенезе которого основную роль играют аутоантитела к внутри- или внеклеточным структурам нервной системы, выступающим в качестве антигенов. Диагности чес кий алгоритм, наряду с проведением комплексного обследования, включающего нейровизуализацию, электроэнцефалографию, исследование цереброспинальной жидкости и определение анти тел к NMDA-рецепторам, еще должен дополняться, в некоторых случаях — поиском онкологических маркеров или очагов. Терапевтический алгоритм АЭ предусматривает комбинированное назначение глюко- кортикостероидной терапии, плазмафереза, иммуноглобулинов, цитостатиков, моноклональных антител, а также — при выявлении в некоторых случаях онкологического процесса — оперативное лечение.
Ключовi слова аутоиммунный энцефалит, NMDA-рецепторы, дифференциальная диагностика, неврологические нарушения, психические нарушения, комбинированное лечение
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